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X-linked dystonia-parkinsonism (XDP) is a severe neurodegenerative disorder caused by a founder retrotransposon insertion, in which a polymorphic hexanucleotide repeat accounts for ~50% of age at onset variability. Employing a genome-wide association study to identify additional factors modifying age at onset, we establish that three independent loci are significantly associated with age at onset. The […]

First one-year longitudinal study of SARS-CoV2 infections yields important findings on infection rates and dynamics, underreporting, risk factors, and impact of lockdown and alleviating measures on infection rates. In the interview with Katrin Neumann (N-TV), Prof. Christine Klein shares the latest findings on the Corona location in Germany and the world. Sources: https://www.n-tv.de/mediathek/videos/panorama/infektionsztszahlen-sinken-impftpepo-bleveltamt-sich-article22566093.html https://www.stern.de/gesundheit/corona-in-Germany–Antuelle-News-zum-coronavirus-in-deutschland–Video–9526032.html

The conference highlights the most cutting-edge long-read sequencing studies with Nanopore technologies.” Please see link for more information:https://nanoporetech.com/lc/resource-centre/university-lubeck-germany

Leonie Schröder is a graduate of the University of Lübeck with a Bachelor´s degree in computational life sciences. Natscha Bahr is a trained media designer. Both new group members will work on the the improvement of our data infrastructure, data quality and safety in the Institute of Neurogenetics and the working group of Meike Kasten.

In 2020, Theresa Lüth completed her master thesis under the supervision of Dr. Joanne Trinh in the group “Integrative Omics Approaches in Parkinson’s Disease” and started as a Ph.D. student this year. During her Ph.D. thesis, she will investigate genetic and environmental modifiers associated with the age at onset of Parkinson’s disease and use the

Prof. Dr. Christine Klein (Foto: © DGN/Tedeskino)

https://youtu.be/cf6o-q7YY_cSource:„DGN/DGN-Kongress 2020“

Neos Cruz is a graduate of the University of the Philippines Diliman with a Bachelor’s degree in Molecular Biology and Biotechnology. He is interested in elucidating the molecular mechanisms underlying neurodegenerative diseases. For his undergraduate thesis, he studied the role of neuron-specific splicing factors in regulating expression of N-TAF1, a gene implicated in X-linked Dystonia

Our institute welcomes Joshua Laß. He is currently a Master’s student in the Molecular Life Sciences program. He is now starting an internship with Dr. Joanne Trinh in the group „Integrative Omics Approaches in Parkinson’s Disease.