Peer-Reviewed Papers

2014

Thomalla G, Jonas M, Bäumer T, Siebner HR, Biermann-Ruben K, Ganos C, Orth M, Hummel FC, Gerloff C, Müller-Vahl K, Schnitzler A, Münchau A. Cost of control – decreased motor cortex engagement during a Go/NoGo task in Tourette syndrome. Brain 2014;137:122-136. IF: 9,5

Ganos C, Zittel S, Minnerop M, Schunke O, Heinbokel C, Gerloff C, Zühlke C, Bauer P, Klockgether T, Münchau A, Bäumer T. Clinical and neurophysiological profile of four german families with spinocerebellar ataxia type 14. Cerebellum. 2014;13:89-96. IF: 2,6

Ganos C, Aguirregomozcorta M, Batla A, Stamelou M, Schwingenschuh P, Münchau A, Edwards MJ, Bhatia KP. Psychogenic paroxysmal movement disorders - Clinical features and diagnostic clues. Parkinsonism Relat Disord 2014;20:41-46. IF: 3,3

David N, Schultz J, Milne E, Schunke O, Schöttle D, Münchau A, Siegel M, Vogeley K, Engel AK. Right Temporoparietal Gray Matter Predicts Accuracy of Social Perception in the Autism Spectrum. J Autism Dev Disord 2014; 44:1433-46 IF: 3,7

Ganos C, Biskup S, Krüger S, Meyer-Osores A, Hodecker S, Hagel C, Schöls L, Bhatia KP, Münchau A. Dystonia with aphonia, slow horizontal saccades, epilepsy and photic myoclonus: A novel syndrome? Parkinsonism Relat Disord 2014;20:328-31. IF: 3,3

Ganos C, Kühn S, Kahl U, Schunke O, Brandt V, Bäumer T, Thomalla G, Haggard P, Münchau A. Prefrontal cortex volume reductions and tic inhibition are unrelated in uncomplicated GTS adults. J Psychosom Res 2014;76:84-87. IF: 3,3

Lohmann K, Schmidt A, Schillert A, Winkler S, Albanese A, Baas F, Bentivoglio AR, Borngräber F, Brüggemann N, Defazio G, Del Sorbo F, Deuschl G, Edwards MJ, Gasser T, Gómez-Garre P, Graf J, Groen JL, Grünewald A, Hagenah J, Hemmelmann C, Jabusch HC, Kaji R, Kasten M, Kawakami H, Kostic VS, Liguori M, Mir P, Münchau A, Ricchiuti F, Schreiber S, Siegesmund K, Svetel M, Tijssen MA, Valente EM, Westenberger A, Zeuner KE, Zittel S, Altenmüller E, Ziegler A, Klein C. Genome-wide association study in musician's dystonia: A risk variant at the arylsulfatase G locus? Mov Disord. 2013 Dec 26. doi: 10.1002/mds.25791. [Epub ahead of print] IF: 4,6

Brüggemann N, Stiller S, Tadic V, Kasten M, Münchau A, Graf J, Klein C, Hagenah J. Non-motor phenotype of dopa-responsive dystonia and quality of life assessment. Parkinsonism Relat Disord. 2014 Apr;20(4):428-31. IF: 3,3

Kumar KR, Lohmann K, Masuho I, Miyamoto R, Ferbert A, Lohnau T, Kasten M, Hagenah J, Brüggemann N, Graf J, Münchau A, Kostic VS, Sue CM, Domingo AR, Rosales RL, Lee LV, Freimann K, Westenberger A, Mukai Y, Kawarai T, Kaji R, Klein C, Martemyanov KA, Schmidt A. Mutations in GNAL: a novel cause of craniocervical dystonia. JAMA Neurol 2014;71:490-4. IF: 7,7

Moll CK, Galindo-Leon E, Sharott A, Gulberti A, Buhmann C, Koeppen JA, Biermann M, Bäumer T, Zittel S, Westphal M, Gerloff C, Hamel W, Münchau A, Engel AK. Asymmetric pallidal neuronal activity in patients with cervical dystonia. Front Syst Neurosci 2014;8:15.

Sharott A, Gulberti A, Zittel S, Tudor Jones AA, Fickel U, Münchau A, Köppen JA, Gerloff C, Westphal M, Buhmann C, Hamel W, Engel AK, Moll CK. Activity parameters of subthalamic nucleus neurons selectively predict motor symptom severity in Parkinson's disease. J Neurosci 2014;34:6273-85. IF: 6,9

Zittel S, Ufer F, Gerloff C, Münchau A, Rosenkranz M. Severe myelopathy after denture cream use - Is copper deficiency or excess zinc the cause? Clin Neurol Neurosurg 2014;121:17-8. IF: 1,2

2013

Lohmann K, Wilcox RA, Winkler S, Ramirez A, Rakovic A, Park JS, Arns B, Lohnau T, Groen J, Kasten M, Brüggemann N, Hagenah J, Schmidt A, Kaiser FJ, Kumar KR, Zschiedrich K, Alvarez-Fischer D, Altenmüller E, Ferbert A, Lang AE, Münchau A, Kostic V, Simonyan K, Agzarian M, Ozelius LJ, Langeveld AP, Sue CM, Tijssen MA, Klein C. Whispering dysphonia (DYT4 dystonia) is caused by a mutation in the TUBB4 gene. Ann Neurol 2013;73:537-545. IF: 11,2

Boelmans K, Kaufmann J, Schmelzer S, Vielhaber S, Kornhuber M, Münchau A, Zierz S, Gaul C. Hirayama disease is a pure spinal motor neuron disorder - a combined DTI and transcranial magnetic stimulation study. J Neurol 2013;260:540-8. IF: 3,6

Buhmann C, Moll CK, Zittel S, Münchau A, Engel AK, Hamel W. Deep brain stimulation of the ventrolateral thalamic base and posterior subthalamic area in dystonic head tremor. Acta Neurochir Suppl 2013;117:67-72. IF: 1,5

Finis J, Enticott PG, Pollok B, Münchau A, Schnitzler A, Fitzgerald PB. Repetitive transcranial magnetic stimulation of the supplementary motor area induces echophenomena. Cortex 2013;49:1978-82. IF: 6,2

HORIZON Investigators of the Huntington Study Group and European Huntington's Disease Network. A randomized, double-blind, placebo-controlled study of latrepirdine in patients with mild to moderate Huntington disease. JAMA Neurol 2013;70:25-33. IF: 7,7

Jung NH, Janzarik WG, Delvendahl I, Münchau A, Biscaldi M, Mainberger F, Bäumer T, Rauh R, Mall V. Impaired induction of long-term potentiation-like plasticity in patients with high-functioning autism and Asperger syndrome. Dev Med Child Neurol 2013;55:83-9. IF: 2,8

Becker F, Schubert J, Striano P, Anttonen AK, Liukkonen E, Gaily E, Gerloff C, Müller S, Heußinger N, Kellinghaus C, Robbiano A, Polvi A, Zittel S, von Oertzen TJ, Rostasy K, Schöls L, Warner T, Münchau A, Lehesjoki AE, Zara F, Lerche H, Weber YG. PRRT2-related disorders: further PKD and ICCA cases and review of the literature. J Neurol 2013;260:1234-44. IF: 3,6

van der Vegt JP, Hulme OJ, Zittel S, Madsen KH, Weiss MM, Buhmann C, Bloem BR, Münchau A, Siebner HR. Attenuated neural response to gamble outcomes in drug-naive patients with Parkinson's disease. Brain 2013;136:1192-203. IF: 9,5

Forkert ND, Schmidt-Richberg A, Treszl A, Hilgetag C, Fiehler J, Münchau A, Handels H, Boelmans K. Automated volumes-of-interest identification for classical and atypical Parkinsonian syndrome differentiation using T2' MR imaging. Methods Inf Med 2013;52:128-36. IF: 1,6

Ganos C, Biskup S, Kleinmichel S, Zittel S, Schunke O, Gerloff C, Münchau A. Progressive ataxia associated with scarring skin lesions and vertical gaze palsy. Mov Disord 2013;28:443-5. IF: 4,6

Hubers AA, van Duijn E, Roos RA, Craufurd D, Rickards H, Bernhard Landwehrmeyer G, van der Mast RC, Giltay EJ; REGISTRY investigators of the European Huntington's Disease Network. Suicidal ideation in a European Huntington's disease population. J Affect Disord 2013;151:248-58. IF: 3,3

Metzger S, Walter C, Riess O, Roos RA, Nielsen JE, Craufurd D; REGISTRY Investigators of the European Huntington’s Disease Network, Nguyen HP. The V471A polymorphism in autophagy-related gene ATG7 modifies age at onset specifically in Italian Huntington disease patients. PLoS One 2013; 22;8:e68951. IF: 3,7

Cheng B, Braass H, Ganos C, Treszl A, Biermann-Ruben K, Hummel FC, Müller-Vahl K, Schnitzler A, Gerloff C, Münchau A, Thomalla G. Altered intrahemispheric structural connectivity in Gilles de la Tourette syndrome. Neuroimage Clin 2013;4:174-81.

2012

Lohmann K, Uflacker N, Erogullari A, Lohnau T, Winkler S, Dendorfer A, Schneider SA, Osmanovic A, Svetel M, Ferbert A, Zittel S, Kühn A, Schmidt A, Altenmüller E, Münchau A, Kamm C, Willstock M, Kupsch A, Moro E, Volkmann J, Kostic V, Kaiser FJ, Klein C, Brüggemann N. Identification and functional analysis of novel THAP1 mutations. Eur J Hum Genet 2012 Feb;20:171-175.

Quarrell OW, Handley O, O'Donovan K, Dumoulin C, Ramos-Arroyo M, Biunno I, Bauer P, Kline M, Landwehrmeyer GB; European Huntington’s Disease Network. Discrepancies in reporting the CAG releat length for Huntington’s disease. Eur J Hum Genet 2012;20:20-26.

Groppa S, Schlaak B, van Nuenen B, Werner-Petroll N, Dünnweber J, Bäumer T, Münchau A, Siebner HR. Probing intrahemispheric connectivity between ipsilateral dorsal premotor and primary motor cortex with ultra-focal dual-site TMS. Hum Brain Mapp 2012;33:419-430.

Franzkowiak S, Pollok B, Biermann-Ruben K, Südmeyer M., Paszek J, Thomalla G. Jonas M, Orth M. Münchau A, Schnitzler A. Motor-cortical interaction in Gilles de la Tourette syndrome. PLoS One 2012;7(1):e27850.

Boelmans K, Holst B, Hackius M, Finsterbusch J, Gerloff C, Fiehler J, Münchau A. Brain iron deposition fingerprints in Parkinson’s disease and progressive supranuclear palsy. Mov Disord 2012 Jan 30. doi: 10.1002/mds.24926. [Epub ahead of print].

Finis J, Moczydlowski A, Pollok B, Biermann-Ruben K, Thomalla G, Heil M, Krause H, Robertson MM, Orth M, Jonas M, Schnitzler A, Münchau A. Echoes from childhood – imitation in Gilles de la Tourette syndrome. Mov Disord 2012 Jan 25. doi: 10.1002/mds.24913. [Epub ahead of print].

Ganos C, Zittel S, Gerloff C, Münchau A, Bäumer T. The complex movement disorder of Kasabach-Merritt syndrome associated with a basal ganglia lesion. Mov Disord 2012 Jan 27. doi: 10.1002/mds.24911. [Epub ahead of print].

Grünewald A, Arns B, Seibler P, Rakovic A, Münchau A, Ramirez A, Sue CM, Klein C. ATP13A2 mutations impair mitochondrial function in fibroblasts from patients with Kufor-Rakeb syndrome. Neurobiol Aging 2012 Jan 30 [Epub ahead of print].

Boelmans K, Gerloff C, Münchau A. Long lasting effect of Levodopa on Holmes’ Tremor. Mov Disord (im Druck).

Schmidt A, Kumar KR, Redyk K, Grünewald A, Leben M, Münchau A, Sue CM, Hagenah J,Hartmann H, Lohmann K, Christen HJ, Klein C. Two faces of the same coin: Infantile seizures and paroxysmal kinesigenic dyskinesia. Arch Neurol (im Druck).

Zittel S, Bester M, Gerloff C, Münchau A, Leypoldt F. Symptomatic paroxysmal kinesigenic choreoathetosis as primary manifestation of multiple sclerosis. J Neurol 2011; 259:557-8.

Zittel S, Kroeger J, van der Vegt JPM, Siebner HR, Brüggemann N, Ramirez A, Behrens MI, Gerloff C, Bäumer T, Klein C, Münchau A. Motor pathway excitability in ATP13A2 mutation carriers. Parkinsonism Relat Disord 2011; 18:590-4.

Lee JM et al. REGISTRY study of the European Huntington's Disease Network, Myers RH; HDMAPS Study Group, MacDonald ME, Gusella JF; COHORT study of the HSG. CAG repeat

expansion in Huntington disease determines age at onset in a fully dominant fashion. Neurology 2012; 78:690-5.

Zittel S, Nickel M, Wolf NI, Uyanik G, Gläser D, Ganos C, Gerloff C, Münchau A, Kohlschütter A."Pelizaeus-Merzbacher-like disease" presenting as complicated hereditary spastic paraplegia. J Neurol 2012; 259:2498-500.

2011

Schmidt A, Jabusch H-C, Altenmüller E, Enders L, Saunders-Pullman R, Bressman SB, Münchau A, Klein C, Hagenah J. Phenotypic spectrum of musician’s dystonia: A task-specific disorder? Mov Disord 2011;26:546-549.

Ganos C, Münchau A, Bäumer T, Gerloff C, Magnus T. 70 years of episodic stiffness – an unsual case of neuromyotonia. Mov Disord 2011; 26:1360-1361.

Zittel S, Bäumer T, Brüggemann N, Gerloff C, Klein C, Münchau A. Paroxysmal cervical myoclonus. Mov Disord 2011 Nov;26:2445-2446.

Schiebler S, Schmidt A, Zittel S, Bäumer T, Gerloff C, Klein C, Münchau A. Arm tremor in cervical dystonia – is it a manifestation of dystonia or essential tremor? Mov Disord 2011;26:1789-1792.

Kamm C, Uflacker N, Asmus F, Schrader C, Wolters A, Wittstock M, Pahnke J, Gasser T, Volkmann J, Münchau A, Hagenah J, Benecke R, Klein C, Lohmann K. No evidence for THAP1/DYT6 mutations as disease modifiers in DYT1 dystonia. Mov Disord 2011;26:2136-2137.

Osmanovic A, Dendorfer A, Erogullari A, Uflacker N, Braunholz D, Rakovic A, Vierke G, Gil-Rodríguez MC, Münchau A, Albrecht M, Brüggemann N, Gillessen-Kaesbach G, Klein C, Lohmann K, Kaiser FJ. Truncating mutations in THAP1 define the nuclear localization signal. Mov Disord 2011;26:1565-1567.

Orth M; European Huntington's Disease Network, Handley OJ, Schwenke C, Dunnett S, Wild EJ, Tabrizi SJ, Landwehrmeyer GB. Observing Huntington’s disease: the European Huntington’s Disease Network’s REGISTRY. J Neurol Neurosurg Psychiatry 2011;82:1409-1412.

Saft C, Epplen JT, Wieczorek S, Landwehrmeyer GB, Roos RA, Garcia de Yebenes J, Dose M, Tabrizi SJ, Craufurd D; Investigators of the European Huntington’s Disease Network. NMDA receptor gene variations as modifiers in Huntington disease: a replication study. PLoS Curr 2011; 3:RRN1247.Van Gaalen J, Pennings RJE, Beynon AJ, Münchau A, Bloem BR, van de Warrenburg B. Cervical dystonia after ear surgery. Parkinsonism Relat Disord 2011 Oct 21. [Epub ahead of print]

Ganos C, Bernreuther C, Matschke J, Gerloff C, Münchau A, Leypoldt F. Ataxia and HIV: Clinicopathological correlations in a case of HIV-associated cerebellar leukoencephalopathy. Cerebellum 2011 Dec 29. [Epub ahead of print]

Leypoldt F, Friese MA, Bohm J, Baumer T (2011) Multiple enlarged nerves on neurosonography: an unusual paraneoplastic case. Muscle Nerve 43: 756-758.

2010

Müller-Vahl K, Dodel I, Müller N, Münchau A, , Reese J-P, Balzer-Geldsetzer M, Dodel R,Oertel W. Health-Related Quality of Life in patients with Gilles de la Tourette syndrome. Mov Disord 2010;25:309-314.

Heise K, Steven B, Liuzzi G, Thomalla G, Jonas M, Müller-Vahl K, Münchau A, Gerloff C,  Hummel FC. Altered modulation of intracortical excitability during movement preparation in Gille de la Tourette syndrome. Brain 2010;133:580-590.

Hasan A, Rothenberger A, Münchau A, Wobrock T, Falkai P, Roessner V. Oral Delta9-tetrahydrocannabinol improved refractory Gilles de la Tourette syndrome in an adolescent by increasing intracortical inhibition: a case report. J Clin Psychopharmacol 2010;30:190-192.

Paszek J, Pollok B, Biermann-Ruben, K, Müller-Vahl K, Roessner V, Thomalla G, Robertson MM, Orth M, Schnitzler A, Münchau A. Is it a tic? – twenty seconds to make a diagnosis. Mov Disord 2010;25:1106-1108.

Jonas M, Thomalla G, Biermann-Ruben K, Siebner HR, Müller-Vahl K, Bäumer T, Gerloff C, Schnitzler A, Orth M, Münchau A. Imitation in patients with Gilles da la Tourette syndrome- a  behavioural study. Mov Disord 2010;25:991-999.

Dodel I, Reese JP, Müller N, Münchau A, Balzer-Geldsetzer M, Wasem J, Oertel W, Dodel R, Müller-Vahl K. Cost of illness in patients with Gilles de la Tourette's syndrome. J Neurol 2010;257:1055-1061.

Franzkowiak S, Pollok B, Biermann-Ruben K, Südmeyer M, Paszek J, Jonas M, Thomalla G, Bäumer T, Orth M, Münchau A, Schnitzler A. Altered pattern of motor cortical activation-inhibition during voluntary movements in Tourette syndrome. Mov Disord 2010;25:1960-1966.

Zittel S, Moll CKE, Brüggemann N, Tadic V, Hamel W, Kasten M, Lohmann K, Lohnau T, Winkler S, Gerloff C, Schönweiler R, Hagenah H, Klein C, Münchau A, Schneider SA. Clinical, neuroimaging and electrophysiological assessment of three DYT6 dystonia families. Mov Disord 2010;25:2405-2412.

Kroeger J, Bäumer T, Jonas M, Rothwell JC, Siebner HR, Münchau A. Charting the excitability of premotor to motor connections while withholding or initiating a selected movement. Eur J Neurosci 2010;32:1771-1779.

Brüggemann N, Hagenah J, Keetz K, Schmidt A, Kasten M,Buchmann I, Eckerle S, Bähre M, Münchau A, Djarmati A, van der Vegt J, Siebner HR, Binkofski F, Ramirez A, Behrens MI, Klein C. Recessively inherited Parkinsonism: effect of ATP13A2 mutations on the clinical and neuroimaging Phenotype. Arch Neurol 2010;67:1357-1363.

Orth M; European Huntington's Disease Network, Handley OJ, Schwenke C, Dunnett SB, Craufurd D, Ho A, Wild EJ, Tabrizi SJ. Observing Huntington's Disease: the European Huntington's Disease Network's REGISTRY. PLoS Curr 2010 Sep 28;2.

Bäumer T, Thomalla G, Kroeger J, Jonas M, Gerloff C, Hummel FC, Müller-Vahl K, Schnitzler A, Siebner HR, Orth M, Münchau A. Interhemispheric motor networks are abnormal in patients with Gilles de la Tourette Syndrom. Mov Disord 2010; 25(16):2828-2837.

2009

Thomalla G, Siebner HR, Jonas M, Bäumer T, Biermann-Ruben K, Hummel F, Gerloff C, Müller-Vahl K, Schnitzler A, Orth M, Münchau A. Structural changes in the somatosensory system correlates with tic severity in Gilles de la Tourette syndrome. Brain 2009;132:765-777. 

Bikmullina R, Bäumer T, Zittel S, MünchauA. Sensory afferent inhibition within and between limbs in humans. Clin Neurophysiol 2009;120:610-618.

Leypoldt F, Münchau A, Moeller F, Bester M, Gerloff C, Heesen C. Hemorrhaging focal encephalitis under fingolimod (FTY720) treatment: A case report. Neurology 2009;72:1022-1024.

Schmidt A, Jabusch H-C, Altenmüller E, Hagenah J, Brüggemann N, Lohmann K, Enders L, Kramer PL, Saunders-Pullman R, Bressman SB, Münchau A, Klein C. Etiology of  musician’s dystonia: Familial or environmental? Neurology 2009;72:1248-1254.

Brüggemann N, Kock N, Lohmann K, König IR, Rakovic A, Hagenah J, Schmidt A, Lohmann K, Jabusch HC, Siebner HR, Altenmüller E, Münchau A, KleinC. The D216H variant in the DYT1 gene: a susceptibility factor for dystonia in familial cases. Neurology 2009;72:1441-1443.

Djarmati A, Schneider SA, Lohmann K, Winkler S, Pawlack H, Hagenah J, Brüggemann N, Zittel S, Raković A, Schmidt A, Jabusch HC, Wilcox R, Kostić VS, Altenmüller E,  Münchau A, Ozelius LJ, Klein C. Mutations in the THAP1 (DYT6) gene – a cause of generalized dystonia with prominent spasmodic dysphonia. Lancet Neurology 2009;8:447-452.

Bäumer T, Hidding U, Hamel W, Buhmann C, Moll CKE, Gerloff C, Orth M, Siebner HR, Münchau A. Effects of DBS, rTMS and l-dopa on motor function and silent period in advanced Parkinson’s disease. Mov Disord 2009; 24:672-676.

Zittel S, Moll CKE, Hamel W, Buhmann C, Engel AK, Gerloff C, Münchau A. Successful GPi deep brain stimulation in a patient with adult onset primary axial dystonia. J Neurol Neurosurg Psychiatry 2009;80:811-812.

Schippling S, Schneider SA, Münchau A, Bhatia KP, Rothwell JC, Tabrizi SJ, Orth M. Short latency afferent inhibition is associated with motor symptom severity in preclinical and very early Huntington’s disease. Biol Psych 2009;65:959-965.

Lencer R, Steinlechner S, Stahlberg J, Rehling H, Orth M, Baeumer T, Rumpf H-J, Meyer C, Klein C, Muenchau A, Hagenah J. Increased risks for psychiatric disorders in primary focal dystonia. J Neuro Neurosurg Psychiatry 2009;80:1176-1179.

Bäumer T, Schippling S, Koch G, Kröger J, Zittel S, Thomalla G, Rothwell JC, Orth M, Münchau A. Inhibitory and facilitatory connectivity from ventral premotor to primary motor cortex in healthy humans at rest - a bifocal TMS study. Clin Neurophysiol 2009;120:1724-1731.

Moll CKE, Sharott A, Hamel W, Münchau A, Buhmann C, Hidding U, Zittel S, Westphal M, Müller D, Engel AK. Waking up the brain. A case study of stimulation-induced wakeful unawareness during anesthesia. Prog Brain Res 2009;177:125-145.

Pötter-Nerger M, Fischer S, Mastroeni C, Groppa S, Deuschl G, Volkmann J, Quartarone A, Münchau A, Siebner HR. Inducing homeostatic-like plasticity in human motor cortex through converging cortico-cortical inputs. J Neurophysiol 2009;102:3180-3190.

Aziz NA, Jurgens CK, Landwehrmeyer GB, van Roon-Mom WM, van Ommen GJ, Stijnen T, Roos RA, Orth M, Handley OJ, Schwenke C, Ho A, Wild EJ, Tabrizi SJ, Landwehrmeyer GB; EHDN Registry Study Group. Normal and mutant HTT interact to affect clinical severity and progression in Huntington disease. Neurology 2009;73:1280-1285.

2008

Grünewald A, Djarmati A, Lohmann-Hedrich K, Farrell K, Zeller JA, Allert N, Papengut F, Petersen B, Fung V, Sue C, O’Sullivan D, Mahant N, Kupsch A, Chuang RS, Wiegers K, Pawlack H, Hagenah J, Ozelius LJ, Stephani U, Schuit R, Lang AE, Volkmann J, Münchau A, Klein C. Myoclonus-dystonia: significance of large SGCE deletions. Hum Mutation 2008;29:331-332. 

Biermann-Ruben K, Kessler K, Jonas M, Siebner HR, Bäumer T, Münchau A, Schnitzler A. Right hemisphere contributions to imitation tasks. Eur J Neurosci 2008;27:1843-1855.

Boros K, Poreisz C, Münchau A, Paulus W, Nitsche MA. Premotor transcranial direct current stimulation (tDCS) affects primary motor cortex excitability in humans. Eur J Neurosci 2008;27:1292-1300.

Seibler P, Djarmati A, Langpap B, Hagenah J, Schmidt A, Brüggemann N, Siebner HR, Jabusch H-C, Altenmüller E, Münchau A, Lohmann K, Klein C. A heterozygous frameshift mutation in the PRKRA (DYT16) gene associated with generalized dystonia in a German patient. Lancet Neurology 2008;7:380-381.

Klöppel S, Bäumer T, Kroeger J, Koch MA, Büchel C, Münchau A, Siebner HR. The cortical motor threshold reflects microstructural properties of cerebral white matter. NeuroImage 2008;40:1782-1791.  

Koch G, Schneider S, Bäumer T, Franca M, Münchau A, Cheeran B, Fernandez  Del Olmo M, Cordivari C, Rounis E, Caltagirone C, Bhatia K, Rothwell JC. Altered dorsal premotor-motor interhemispheric pathway activity in focal arm dystonia. Mov Disord 2008;23:660-668.

Orth M, Münchau A, Rothwell JC. Corticospinal system excitability at rest is associated with tic severity in Tourette syndrome. Biol Psych 2008;64:248-251.

Weber YG, Storch A, Wuttke TV, Brockmann K, Kempfle J, Maljevic S, Margari L, Kamm C, Schneider SA, Huber SM, Pekrun A, Roebling R, Seebohm G, Koka S, Lang C, Kraft E,  Blazevic D, Salvo-Vargas A, Fauler M, Mottaghy FM, Münchau A, Edwards MJ, Presicci A, Margari F, Gasser T, Lang F, Bhatia KP, Lehmann-Horn F, Lerche H. GLUT1 mutations are a cause of paroxysmal exertion-induced dyskinesiasand a cation leak of this glucose transporter is linked to hemolytic anemia. J Clin Invest 2008; 118(6):2157-2168.

Moll CKE, Hamel W, Ostertag CB, Müller D, Finsterbusch J, Engel AK, Münchau A. Subthalamotomy in cervical dystonia: a case study of lesion location and clinical outcome. Mov Disord 2008;23:1751-1756.

Biermann-Ruben K, Jonas M, Kessler K, Siebner HR, Bäumer T, Schnitzler A, Münchau A. Observing repetitive finger movements modulates response times of auditorily cued finger movements. Brain Cognition 2008;68:107-113.

Schippling S, Orth M, Beisiegel U, Rosenkranz T, Vogel P, Münchau A, Hagel C, Seedorf U. Severe Tangier disease with a novel ABCA1 gene mutation. Neurology 2008;71:1454-1455.

Zittel S, Weiller C, Liepert J. Citalopram improves dexterity in chronic stroke patients. Neurorehabil Neural Repair 2008; 22:311-4.

Lehmann W, Ushmaev A, Ruecker A, Nuechtern J, Grossterlinden L, Begemann PG, Baeumer T, Rueger JM, Briem D. Comparison of open versus percutaneous pedicle screw insertion in a sheep model. Eur Spine J 2008; 17: 857-863.

2007

Bäumer T, Demiralay J, Hidding U, Bikmullina R, Helmich R, Wunderlich S, Rothwell J,Liepert J, Siebner HR, Münchau A. Abnormal plasticity of the sensorimotor cortex to slow repetitive transcranial magnetic stimulation in patients with writer's cramp. Mov Disord 2007;22:81-90.

Hiller A, Hagenah JM, Djarmati A, Hedrich K, Reetz K, Schneider-Gold C, Kress W, Münchau A, Klein C. Phenotypic spectrum of PINK1-associated parkinsonism in 15 mutation carriers from one family. Mov Disord 2007; 22:145-147.

Klöppel S, v. Eimeren T, Glauche V, Vongerichten A, Münchau A, Frackowiak RS, Büchel C, Weiller C, Siebner HR. The effect of handedness on cortical motor activation during simple bilateral movements. NeuroImage 2007;34:274-280.

Lewerenz J, Ding X-Q, Matschke J, Schnabel C, Emami P, von Borczyskowski D, Buchert R, de Wit M, Münchau A. Dementia and leukoencephalopathy due to lymphomatosis cerebri - Report of two cases. J Neurol Neurosurg Psychiatry 2007;78:777-778.

Jonas M, Biermann-Ruben K, Kessler K, Lange R, Bäumer T, Siebner HR, Schnitzler A, Münchau A. Observation of a finger or an object movement primes imitative responses differentially. Exp Brain Res 2007;177:255-265.

Zeuner KE, Peller M, Knutzen A, Holler I, Münchau A, Hallett M, Deuschl G, Siebner HR. Handwriting and drawing movements are altered in patients with writer’s cramp but show no correlation with clinical rating scales. Mov Disord 2007;22:1102-1109.

Brashear A, Dobyns WB, de Carvalho Aguiar P, Borg M, Frijns CJM, Gollamudi S, Green A, Guimaraes J, Haake BC, Klein C, Linazasoro G, Münchau A, Raymond D, Riley D, Tijssen MAJ, Zaremba J, Bressman SB, Ozelius LJ. The Phenotypic Spectrum of Rapid-Onset Dystonia-Parkinsonism (RDP) Associated With Mutations In The ATP1A3 Gene. Brain 2007;130:828-835.

Grünewald A, Breedveld GJ, Hedrich K, Rohé CF, König IR, Hagenah J, Vanacore N, Meco G, Antonini A, Goldwurm S, Lesage S, Dürr A, Binkofski F, Siebner HR, Münchau A, Brice A, Oostra B, Klein C, Bonifati V, Biological effects of the PINK1 c.1366C>T mutation: Implications in Parkinson disease pathogenesis. Neurogenetics 2007;8:103-109.

Bäumer T, Dammann E, Bock F, Klöppel S, Siebner H, Münchau A. Laterality ofinterhemispheric inhibition depends on handedness. Exp Brain Res 2007;180:195-203.

Jonas M, Siebner HR, Biermann-Ruben K, Kessler K, Bäumer T, Büchel C, Schnitzler A,Münchau A. Do simple intransitive finger movements consistently activate fronto-parietal mirror neuron areas in humans? NeuroImage 2007;36(Suppl 2):T44-53.

Bäumer T, Pramstaller PP, Schippling S, Hagenah J, Peller M, Siebner HR, Gerloff C, Klein C, Münchau A. Sensorimotor integration is abnormal in asymptomatic Parkin mutation carriers – a TMS study. Neurology 2007;69:1976-1981.

Orth M, Djarmati A, Bäumer T, Winkler S, Grünewald A, Lohmann-Hedrich K, Kabakci K, Hagenah J, Klein C, Münchau A. Autosomal dominant myoclonus-dystonia and Tourette syndrome in a family without linkage to the SGCE gene. Mov Disord 2007;22:2090-2096.

Zittel S, Weiller C, Liepert J. Reboxetine improves motor function in chronic stroke. A pilot study. J Neurol 2007; 254:197-201.

Zittel S, Baumer T, Liepert J. Modulation of intracortical facilitatory circuits of the human primary motor cortex by digital nerve stimulation. Exp Brain Res 2007; 176:425-31.

Liepert J, Zittel S, Weiller C. Improvement of dexterity by single session low-frequency repetitive transcranial magnetic stimulation over the contralesional motor cortex in acute stroke: a double-blind placebo-controlled crossover trial. Restor Neurol Neurosci 2007; 25:461-5.

2006

van Eimeren T, Wolbers T, Münchau A, Büchel C, Weiller C, Siebner HR. Implementationof visuospatial cues in response selection. NeuroImage 2006;29:286-294.

Hedrich K, Hagenah H, Djarmati A, Hiller A, Lohnau T, Lasek K, Grünewald A, Hilker R,Steinlechner S, Boston H, Kock N, Schneider-Gold C, Kress W, Siebner H, BinkofskiF, Lencer R, Münchau A, Klein C. Clinical spectrum of homo- and heterozygous PINK1 mutations in a large German family with Parkinson´s disease: Role of a single hit? Arch Neurol 2006;63:833-838.

Bäumer T, Bock F, Koch G, Lange R, Rothwell JC, Siebner HR, Münchau A. Magnetic stimulation of human premotor or motor cortex produces interhemispheric facilitation through distinct pathways. J Physiol 2006;572:857-868.

Leypoldt F, Eichhorn P, Saager C, Münchau A, Lewerenz J. Successful immunosuppressive treatment and long term follow-up of anti-Ri associated paraneoplastic myelitis. J Neurol Neurosurg Psychiatry 2006;77:1199-1200.

Hidding, U, Bäumer, T, Siebner, HR, Demiralay C, Buhmann, C, Hamel W, Münchau A. MEP latency shift after implantation of deep brain stimulation systems in the subthalamic nucleus in patients with advanced Parkinson’s disease. Mov Disord 2006 21:1471-1476.

Peller M, Zeuner KE, Münchau A, Quartarone A, Weiß M, Knutzen A, Hallett M,Deuschl G, Siebner HR. The basal ganglia are overactive during the discrimination of tactile stimuli in writer’s cramp. Brain 2006;129:2697-708.

Kessler K, Biermann-Ruben K, Jonas M, Siebner HR, Bäumer T, Münchau A, Schnitzler A. Investigating the human mirror neuron system by means of cortical synchronization during the imitation of biological movements. NeuroImage 2006;33:227-238.

2005

Helmich RCG, Bäumer T, Siebner HR, Bloem BR, Weiller C, Münchau A. Hemispheric asymmetry and somatotopy of afferent inhibition in healthy humans. Exp Brain Res 2005;167:211-219.

Lewerenz J, Zurowski B, Bäumer T, Lees AJ, Münchau A. Is axial rigidity in extension in PSP unrelated to nigrostriatal dopamine deficiency? Mov Disord 2005;20:1071-1075.

Liepert J, Restemeyer C, Münchau A, Weiller C. Motor cortex excitability after thalamic Infarction. Clin Neurophysiol 2005;116:1621-1627.

Münchau A, Langosch JM, Gerschlager W, Rothwell JC, Orth M, Trimble MR. Mirtazapine increases cortical excitability in healthy controls and epilepsy patients with major depression. J Neurol Neurosurg Psychiatry 2005;76:527-533.

Orth M, Kirby R, Richardson M, Snijders AH, Rothwell JC, Trimble MR, Robertson MM, Münchau A. Repetitive transcranial magnetic stimulation has no effect on tics in patients with Gilles de la Tourette syndrome. Clin Neurophysiol 2005;116:764-768.

Snijders AH, Bloem BR, Orth M, Rothwell JC, Trimble MR, Robertson MM, Münchau A. Video assessment of rTMS for Tourette syndrome (letter). J Neurol Neurosurg Psychiatry 2005;1743-1744.

Liepert J, Restemeyer C, Kucinski T, Zittel S, Weiller C. Motor strokes: the lesion location determines motor excitability changes. Stroke 2005; 36:2648-53.

Liepert J, Mingers D, Heesen C, Baumer T, Weiller C (2005) Motor cortex excitability and fatigue in multiple sclerosis: a transcranial magnetic stimulation study. Mult Scler 11: 316-321.

2004

Rizzo V, Siebner HR, Modugno N, Pesenti A, Münchau A, Gerschlager W, Webb RM,  Rothwell JC. Shaping the excitability of human motor cortex with premotor rTMS. J Physiol 2004;554.2:483-495.

Kock N, Kasten M, Schüle B, Hedrich K, Wiegers K, Kabakci K, Hagenah J, Pramstaller PP, Nitschke MS, Münchau A, Sperner J, Klein C. Clinical and genetic features of Myoclonus-Dystonia in 3 cases: a video presentation. Mov Disord 2004;19:231-234.

Peinemann A, Reimer B, Löer C, Quartarone A,  Münchau A, Conrad B,  Siebner HR. Long-lasting increase in corticospinal excitability after 1800 pulses of subthreshold 5 Hz repetitive TMS to the motor cortex. Clin Neurophysiol 2004;1519-1526.

Gerschlager W, Münchau A, Katzenschlager R, Brown P, Rothwell JC, Quinn N, Lees AJ, Bhatia KP. Natural history and syndromic associations of orthostatic tremor: a review of 41 patients. Mov Disord 2004;19:788-795.

Gorsler A, Zittel S, Weiller C, Münchau A, Liepert J. Modulation of motor cortex excitability induced by pinch grip repetition. J Neural Transm 2004;111:1005-1016.

Buhmann C, Gorsler A, Bäumer T, HiddingU, Demiralay C, Hinkelmann K, Weiller C, Siebner HR, Münchau A. Abnormal plasticity of premotor-to-motor connections in de novo Parkinson’s disease. Brain 2004;127:2732-2746.

2003

Bäumer T, Lange R, Liepert J, WeillerC, Siebner H, Rothwell JC, Münchau A. Repeated premotor rTMS leads to cumulative plastic changes of motor cortex excitability in humans. NeuroImage 2003;20:550-560.

Liepert J, Gorsler A, van Eimeren T, Münchau A, Weiller C. Motor excitability in a patient with a somatosensory cortex lesion. Clin Neurophysiol 2003;114:1003-1008.

Gorsler AC, Bäumer T, Weiller C, Münchau, A, Liepert J. Interhemispheric effects of high and low frequency rTMS in healthy humans. Clin Neurophysiol 2003;114;1800-1807.

Schlaghecken F, Münchau A, Bloem BR, Rothwell JC, Eimer M. Slow frequency repetitive transcranial magnetic stimulation affects reaction times, but not priming effects, in a masked prime task. Clin Neurophysiol 2003;114:1272-1277.

Hamzei F, Rijntjes M, Gbadamosi J, Fuchs K, Weiller C, Münchau A. Life-threatening respiratory failure due to cranial dystonia after dental procedures in a patient with multiple system atrophy. Mov Disord 2003;18:959-961.

Gbadamosi J, Münchau A, Weiller C, Schäfer H. Severe heart failure in a young multiple sclerosis patient. J Neurol 2003:250:241-242.

Stuerenburg HJ, Petersen K, Buhmann C, Rosenkranz M, Baeumer T, Thomasius R. Plasma amino acids in ecstasy users. Neuro Endocrinol Lett 2003; 24: 348-349.

2002

Münchau A, Orth M, Rothwell JC, Di Lazzaro V, Oliviero A, Profice P, Tonali P, Pramstaller PP, Bhatia KP. Intracortical inhibition is reduced in a patient with a lesion in the posterolateral thalamus. Mov Disord 2002;17:208-212.

Münchau A, Bloem BR, Irlbacher K, Trimble MR, Rothwell JC. Functional connectivity of human premotor and motor cortex explored with repetitive transcranial magnetic stimulation. J Neurosci 2002;22:554-561.

Dressler D, Münchau A, Bhatia KP, Quinn NP, Bigalke H. Antibody-induced botulinum toxin therapy failure: can it be overcome by increased botulinum toxin doses? EurNeurol 2002;47:118-121.

Tijssen MAJ, Münchau A, Marsden JF, Lees A,  Bhatia KP, Brown, P. Descending control of muscles in patients with cervical dystonia. Mov Disord 2002;17:3:493-500.

Bäumer T, Münchau A, Weiller C, Liepert J. Fatigue suppresses ipsilateral intracortical Facilitation. Exp Brain Res 2002;146:467-473.

Münchau A, Bloem BR, Thilo KV, Trimble MR, Rothwell JC, Robertsen. Repetitive transcranial magnetic stimulation for Tourette syndrome. Neurology 2002;59:1789-1790.

Stuerenburg HJ, Petersen K, Baumer T, Rosenkranz M, Buhmann C, Thomasius R. Plasma concentrations of 5-HT, 5-HIAA, norepinephrine, epinephrine and dopamine in ecstasy users. Neuro Endocrinol Lett 2002; 23: 259-261.

2001

Münchau A, Corna S, Gresty M, Bhatia KP, Palmer JD, Dressler D, Quinn NP, Rothwell JC, Bronstein AM. Abnormal interaction between vestibular and voluntary head control in patients with spasmodic torticollis. Brain 2001;124:47-59.

Münchau A,  Palmer JD, Dressler D, O’Sullivan J, Tsang KL, Jahanshahi M, QuinnNP, Lees AJ, Bhatia KP. Prospective study of selective peripheral denervation for botulinum-toxin resistant patients with cervical dystonia. Brain 2001;124:769-783.

Münchau A, Bahlke G, Allen PJ, Quinn NP, Lees AJ, Rothwell JC, Palmer CD, Bhatia KP. Polymyography combined with time-locked video recording (video EMG) for presurgical assessment of patients with cervical dystonia. Eur Neurol 2001;45:222-228.

Münchau A, Good CD, MacGowan S, Quinn NP, Palmer JD, Bhatia KP. Prospective study of swallowing function in patients with cervical dystonia undergoing selective peripheral denervation. J Neurol Neurosurg Psychiatry 2001;71:67-72.

Münchau A, Schrag A, Chuang C, McKinnan C, Bhatia KP, Quinn NP, Rothwell JC. Arm tremor in cervical dystonia differs from essential tremor and can be classified by onset age and spread of symptoms. Brain 2001;124:1765-1776.

Münchau A, Filipović SR, Oester-Barkey A,  Quinn NP, Rothwell JC, Bhatia KP.  Spontaneously changing muscular activation pattern in patients with cervical dystonia Mov Disord 2001;16:1091-1097.

2000

Chawda SJ, Münchau A, Johnson D, Bhatia K, Quinn NP, Stevens J, Palmer JD. The pattern of premature degenerative changes of the cervical spine in patients with spasmodic torticollis and the impact on the outcome of selective peripheral denervation. J Neurol Neurosurg Psychiatry 2000;68:465-471.

Münchau A, Valente EM, Shahidi GA, Quinn NP, Eunson L, Hanna M, Wood N, Bhatia KP. A new family with paroxysmal exercise-induced dystonia and associated migraine. J Neurol Neurosurg Psychiatry 2000;68:609-614.

Münchau A , Rosenkranz T. Benign monomelic amyotrophy of lower limb. Case report and review of the literature. Eur Neurol 2000;43:238-240.

Münchau A, Mathen D, Cox T, Quinn NP, Marsden CD, Bhatia KP. Isolated unilateral lesions of the globus pallidus: report of four patients presenting with focal or segmental dystonia. J Neurol Neurosurg Psychiatry 2000;69:494-498.

Münchau A, Valente EM, Wood NW, Quinn NP, Bhatia KP. A Yorkshire family with adult-onset cranio-cervical primary torsion dystonia. Mov Disord 2000;15:954-959.

Peinemann A, Lehner C, Mentschel C, Münchau A, Conrad B, Siebner HR. Subthreshold 5-Hz repetitive transcranial magnetic stimulation of the human primary motor cortex reduces intracortical paired-pulse inhibition. Neurosci Lett 2000;296:21-24.

Schrag A, Münchau A, Quinn NP, Bhatia KP, Marsden CD. Essential tremor. An overdiagnosed condition? J Neurol 2000;247:955-959.

Vor 2000

Muenchau A, Laas R. Xanthogranuloma and xanthoma of the choroid plexus: evidence for different etiology and pathogenesis. Clin Neuropathol 1997;1­6:72-76.

Münchau A, Hagel C, Vogel P. Adrenoleukodystrophy of very late onset. J Neurol 1997;244(9):595-599.

Münchau A, Dressler D, Bhatia KP, Vogel P, Zühlke C. Machado-Joseph disease presenting as severe generalised dystonia in a German patient. J Neurol 1999;246:840-842.

Schrag A, Muenchau A, Bhatia KP, Quinn NP, Marsden CD. Overdiagnosis of essential tremor (letter). Lancet 1999;353:1498-1499.

Bhatia KP, Münchau A, Brown P. Botulinum toxin is a useful treatment in excessivedrooling of saliva (letter). J Neurol Neurosurg Psychiatry 1999;67:697.

Bhatia KP, Münchau A, Thompson PD, Houser M, Chauhan VS, Hutchinson M, Shapira AHV, Marsden CD. Generalised muscular weakness following botulinum toxin injections for dystonia: a report of 3 cases. J Neurol Neurosurg Psychiatry 1999;67:90-93.

Münchau A, Vogel P. Reversible posterior encephalopathy, possibly related to coeliac disease – a vitamin depleted brain? Eur Neurol 1999;41:232-234.

Mellies JK, Baumer T, Muller JA, Tournier-Lasserve E, Chabriat H, Knobloch O, Hackelöer HJ, Goebel HH, Wetzig L, Haller P. SPECT study of a German CADASIL family: a phenotype with migraine and progressive dementia only. Neurology 1998; 50: 1715-1721.