Alexander Münchau
Alexander Münchau, MD
Section Head
Phone number:+49 451 290 3422

Personal Information

Name: Alexander Münchau

Date of Birth: June 10th, 1966

Place of Birth: Hamburg, Germany

Position/Title: Full Professor of Neurology and Neuropsychiatry, Head of Paediatric and Adult Movement Disorders and Neuropsychiatry Group; Institute of Neurogenetics, University of Lübeck, Speaker of the Lübeck Centre for Rare Diseases 

Address: Paediatric and Adult Movement Disorders and Neuropsychiatry Group, Institute of Neurogenetics, University of Lübeck, Maria-Goeppert-Strasse 1, 23562 Lübeck, Germany

Phone: +49-451-2903422; Fax: +49-451-2903423
Email: alexander.muenchau@neuro.uni-lübeck.de

Education/Position

1971-1976: Primary school 

1976-1985: Grammar school

1987-1990: Medical Faculty of the Freie Universität Berlin

1990-1993: Medical Faculty of the Universität Hamburg

1993: Third Medical Examination (Staatsexamen)

07.1995: Full registration with the Medical Council of Hamburg

1997: Electromyography and Electroencephalography certificate

07.01: Qualification as Neurologist

07.01-08.02: Specialist training on a neurological intensive care unit

08.02-11.02: Specialist training in neurological ultrasound

04.05: Teaching permission for evoked potential studies, EEG and EMG of the Deutsche Gesellschaft für Klinische Neurophysiologie                   

Work Experience

1994-1997: Training in Clinical Neurology and Neurophysiology in the Department of Neurology and Neurophysiology of St. Georg Hospital in Hamburg under the supervision of Professor Peter Vogel

1998-2000: Research Fellow to Professor Niall P Quinn at the National Hospital for Neurology and Neurosurgery and to Dr Adolfo Bronstein and Dr John Rothwell at the Human Movement and Balance, Institute of Neurology, Queen Square, London, UK

2000-2001: Research Fellow to Professor Michael Trimble in the Department of Neuropsychiatry, National Hospital for Neurology and Neurosurgery and to Dr. John Rothwell in the Human Movement and Balance Unit, Institute of Neurology, Queen Square, London, UK   

2001-2003: Registrar in the Neurology Department of the University Medical Centre Hamburg-Eppendorf, Germany; Head of Movement Disorder Research Group

2003-2013: Consultant Neurologist in the aforementioned Department; Head of Movement Disorder Research Group

Memberships and Academic Activities

Deutsche Gesellschaft für Neurologie (DGN)

Neurowissenschaftliche Gesellschaft

International Federation of Clinical Neurophysiology

International Movement Disorders Society

Deutsche Dystonie-Gesellschaft

Tourette Gesellschaft Deutschland

Arbeitskreis Botulinumtoxin e.V. der DGN

N.E.MO. Förderverein für die Erforschung der Neurophysiologie und Entwicklung des Motorischen Systems und die Erforschung und Behandlung von Bewegungsstörungen bei Kindern, Jugendlichen und Erwachsenen e.V.

 

Speaker of the Lübeck Center for Rare Disease (since 2013)

Member of the Scientific Advisory Board of the Tourette Gesellschaft Deutschland (since 2006)

Chairman of the N.E.MO. Charity (since 2007)

Member of the „Agency of Surplus“ (Art - Performance Group) (since 2010) 

Current FUNDING

2011-2015; € 320.000   Project “Connectivity and plasticity in cortical motor networks in Parkin gene associated                                                    parkinsonism and dopa-responsive dystonia” as part of the Sonderforschungsbereich SFB 936                                             “Multi-Site Communication in the Brain”

2011-2015; € 150.000   Collaborative research project „European Multicentre Tics in Children Studies (EMTICS)“, in the                                          FP7 programme (HEALTH.2011.2.2.1-3: Addictive and/or compulsive behaviour in children and                                            adolescents: translating pre-clinical results into therapies)

2014-2015; € 50.000     Research support of the University of Lübeck for the project „Longitudinal inverstigation of                                                cortico-cortical conectivity in de novo Parkinson patients“.

Memberships and academic activities

Deutsche Gesellschaft für Neurologie (DGN)

Neurowissenschaftliche Gesellschaft

International Federation of Clinical Neurophysiology

International Movement Disorders Society

Deutsche Dystonie-Gesellschaft

Tourette Gesellschaft Deutschland

Arbeitskreis Botulinumtoxin e.V. der DGN

N.E.MO. Förderverein für die Erforschung der Neurophysiologie und Entwicklung des Motorischen Systems und die Erforschung und Behandlung von Bewegungsstörungen bei Kindern, Jugendlichen und Erwachsenen e.V.

 

Speaker of the Lübeck Center for Rare Disease (since 2013)

Member of the Scientific Advisory Board of the Tourette Gesellschaft Deutschland (since 2006)

Chairman of the N.E.MO. Charity (since 2007)

Member of the „Agency of Surplus“ (Art - Performance Group) (since 2010) 

Publications

Five most important publications: 

Münchau A, Bloem BR, Irlbacher K, Trimble MR, Rothwell JC. Functional connectivity of human premotor and motor cortex explored with repetitive transcranial magnetic stimulation. J Neurosci 2002;22:554-561.

Bäumer T, Lange R, Liepert J, WeillerC, Siebner H, Rothwell JC, Münchau A. Repeated premotor rTMS leads to cumulative plastic changes of motor cortex excitability in humans. NeuroImage 2003;20:550-560.

Buhmann C, Gorsler A, Bäumer T, HiddingU, Demiralay C, Hinkelmann K, Weiller C, Siebner HR, Münchau A. Abnormal plasticity of premotor-to-motor connections in de novo Parkinson’s disease. Brain 2004;127:2732-2746.

Thomalla G, Siebner HR, Jonas M, Bäumer T, Biermann-Ruben K, Hummel F, Gerloff C, Müller-Vahl K, Schnitzler A, Orth M, Münchau A. Structural changes in the somatosensory system correlates with tic severity in Gilles de la Tourette syndrome. Brain 2009;132:765-777. 

Thomalla G, Jonas M, Bäumer T, Siebner HR, Biermann-Ruben K, Ganos C, Orth M, Hummel FC, Gerloff C, Müller-Vahl K, Schnitzler A, Münchau A. Cost of control – decreased motor cortex engagement during a Go/NoGo task in Tourette syndrome. Brain 2014;137:122-136. 

 

Overview:

Articles (Peer reviewed): 185

Reviews: 20

Book chapters: 19

Guidlines: 6

Editorials: 8

 

Cumulative Impact Factor:   833    
Mean Impact factor:             4,5

H- Factor:                             34

Reviewer Activities

Journals

  • Annals of Neurology
  • Brain
  • Cerebral Cortex
  • Current Biology
  • Clinical Neurophysiology
  • European Journal of Neurology
  • Experimental Brain Research
  • European Journal of Medical Genetics
  • JAMA
  • Journal of Neurophysiology
  • Journal of Psychiatry and Neuroscience
  • Lancet Neurology
  • Lancet Psychiatry
  • Movement Disorders
  • Neuroscience Research
  • Neuroreports
  • Neuroscience Letters

Grants

  • German Research Foundation (DFG)
  • Studienstiftung des Deutschen Volkes
  • University of Lübeck
National and International Co-operation

Klinik für Neurologie, Universität zu Lübeck (Professor Münte, Professor Krämer, Dr. Bahlmann, Dr. Heldmann)

Max-Planck-Institut für Bildungsforschung, Berlin (Professor Kühn, Dr. Verrel)

Klinik für Psychiatrie, Sozialpsychiatrie und Psychotherapie Medizinische Hochschule Hannover (Professor Müller-Vahl)

Klinik und Poliklinik für Kinder- und Jugendpsychiatrie und Psychotherapie Universitätsklinikum Carl Gustav Carus an der Technischen Universität Dresden (Professor Roessner, Professor Beste)

Institute of Cognitive Neuroscience, University College London
(Professor Haggard)

Department of Experimental Psychology University of Gent
(Professor Brass)

Danish Research Centre for Magnetic Resonance Copenhagen University Hospital Hvidovre (Professor Siebner)

University Psychiatric Centre, Faculty of Medical Sciences, Groningen, The Netherlands (Professor Pieter Hoekstra) 

Clinical Trials

- 2000-2001 Kyowa study (Phase 2 clinical study on Adenosine Antagonist as a treatment for Parkinson patients), National Hospital for Neurology and Neurosurgery, Queen Square, London (Research Fellow)

- 2006-2007 Amarin study (Phase 3 clinical study on Miroxione as a treatment of motor symptoms in patients with Huntington’s disease), Klinik und Poliklinik für Neurologie am UKE (PI)

- 2009-11: Medivation Dimebon study (Phase 3 clinical study on the efficacy of Dimebon as a treatment of motor and non-motor symptoms in patients with Huntington’s disease, Klinik und Poliklinik für Neurologie am UKE (independent rater)

- 2006-2013 Registry study of the European Huntington Network, Klinik und Poliklinik für Neurologie am UKE (PI); University of Lübeck (PI)

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