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Completed grants

“Molecular biology of early-onset Parkinson’s disease“

Principal Investigator: Christine Klein, MD
Funding Agency: German Research Foundation (DFG)
Funding period: 1999-2002
Amount: 150,000 €

“Molecular genetics of dystonia“

Principal Investigator: Christine Klein, MD
Funding Agency: German Dystonia Foundation
Funding period: 1999-2001
Amount: 8,500 €

“Competence Network Parkinson’s Disease“

Principal Investigator: Christine Klein, MD
Funding Agency: Federal Ministry of Education and Research (BMBF)
Funding period: 2000-2004
Amount: 200,000 €

“Genetics of myoclonus-dystonia“

Principal Investigator: Christine Klein, MD
Funding Agency: Fritz Thyssen Foundation
Funding period: 2000-2003
Amount: 100,000 €

“Frequency of Parkin mutations in Parkinson’s disease“

Principal Investigator: Christine Klein, MD
Funding Agency: Parkinson Disease Foundation (USA)
Funding Period: 2001-2002
Amount: 30,000 €

“Molecular Etiology of early-onset parkinsonism”

Principal Investigator: Christine Klein, MD
Funding Agency: German Research Foundation (DFG)
Funding period: 2002-2004
Amount: 250,000 €

“Clinical, genetic, and PET studies of DJ-1-associated early-onset parkinsonism”

Principal Investigator: Christine Klein, MD
Funding Agency: Parkinson Disease Foundation/National Parkinson Foundation (USA)
Funding period: 2003-2004
Amount: 30,000 €

“Molecular and epigenetic investigation of myoclonus-dystonia”

Principal Investigator: Christine Klein, MD
Funding Agency: Fritz Thyssen Foundation
Funding period: 2003-2005
Amount: 100,000 €

“Heisenberg Fellowship“

Principal Investigator: Christine Klein, MD
Funding Agency: German Research Foundation (DFG)
Funding period: 2003-2005
Amount: 131,000 €

“Molecular genetic analysis of dopa-responsive dystonia and penetrance studies”

Principal Investigators: Christine Klein, MD and Katja Lohmann, PhD
Funding Agency: Edith Fröhnert Foundation
Funding period: 2005-2007
Amount: 45,000 €

“W2 Lichtenberg Professorship (Associate professor)“

Principal Investigator: Christine Klein, MD
Funding Angency: Volkswagen Foundation
Funding period: 2005-2010
Amount: 1,300,000 €

“Infrastructure support of the Lichtenberg Grant“

Principal Investigator: Christine Klein, MD
Funding Angency: Possehl Foundation
Funding period: 2005-2011
Amount: 77,000 €

“Scholarship for Eastern European scientists (DYT8 dystonia)”

Principal Investigator: Christine Klein, MD
Funding Agency: German Research Foundation (DFG)
Funding period: 2005-2006
Amount: 16,300 €

“Genetic risk factors of musician´s dystonia as a special subgroup of focal dystonia”

Principal Investigator: Christine Klein, MD
Funding Agency: Dystonia Medical Research Foundation
Funding period: 2006
Amount: 40,000 €

“Impact of mutations in Parkin and PINK1: Endogenous protein function in Parkinson disease”

Principal Investigators: Christine Klein, MD and Norman Kock, MD 
Funding Agency: Fritz Thyssen Foundation
Funding period: 2006-2008
Amount: 140,000 €

„Identifying the genetic etiology of restless legs syndrome”

Principal Investigators: Katja Lohmann, PhD and Christine Klein, MD
Funding Agency: German Research Foundation (DFG)
Funding period: 2007-2009
Amount: 160,000 €

“Genomic biomarkers for Parkinson's disease”

Principal Investigator: Christine Klein, MD
Funding Agency: European Commission (EU)
Funding period: 2007-2011
Amount: 440,000 €

“Interdisciplinary Center for Genetic Movement Disorders Lübeck”

Principal Investigator: Christine Klein, MD
Funding Agency: Possehl Foundation
Funding period: 2007-2012
Amount: 388,000 €

“Graduate School for Computing in Medicine and Life Sciences” (GSC 235)

Principal Investigator: Christine Klein, MD
Funding Agency: German Research Foundation (DFG Program of Excellence)
Funding period: 2007-2012 
Amount: 150,000 €

“The biochemical consequences of the C1366T PINK1 mutation in PD patient and mutation carrier cells”

Principal Investigators: Anthony H.V. Shapira, PhD and Christine Klein, MD
Funding agency: Parkinson's Disease Society UK
Funding period: 2008
Amount: 15,000 €

“Family studies of ATP13A2-associated parkinsonism”

Principal Investigator: Christine Klein, MD
Funding agency: Hilde Ulrichs Foundation for Parkinson’s Disease
Funding period: 2008
Amount: 10,000 €

“Support for the 14. Annual Meeting of the German Society of Neurogenetics in Lübeck“

Principal Investigator: Christine Klein, MD
Funding agency: German Research Foundation (DFG)
Funding period: 2008
Amount: 2,630 €

“Role of the PRKRA (DYT16) gene in dystonia”

Principal Investigator: Christine Klein, MD and Ana Djarmati, PhD
Funding agency: German Research Foundation (DFG)
Funding period: 2008-2010
Amount: 102,000 €

”Support of a bilateral collaboration with Pakistan”

Principal Investigator: Prof. Dr. Christine Klein
Funding agency: German Research Foundation (DFG)
Funding period: 2010
Amount: 5,000 €

“Genetic risk factors of musician’s dystonia”

Principal Investigators: Katja Lohmann, PhD, Christine Klein, MD, and Andreas Ziegler, PhD
Funding agency: German Research Foundation (DFG)
Funding period: 2010-2011
Amount: 295,000 €

“Identification of the mutated genes in two novel forms of hereditary spastic paraplegia”

Principal Investigator: Alfredo Ramirez, PI
Funding Agency: Tom Wahlig Stiftung
Funding period: 2010-2011
Amount: 15,000 €

“The role of Parkin in mitochondrial function and morphology”

Principal Investigator: Anne Grünewald, PhD
Funding agency: German Research Foundation (DFG)
Funding period: 2010-2011
Amount: 95,000 €

“Parkin-mediated ubiquitination and Parkinson´s disease: Role of ubiquitin-conjugating enzymes (E2s) and ubiquitin-interacting motif (UIM)-containing proteins”

Principal Investigator: Ana Djarmati, PhD
Funding agency: German Research Foundation (DFG)
Funding period: 2010-2011
Amount: 30,540 €

“Elucidation of the genetic cause of DYT4 using exome sequencing”

Principal Investigator: Christine Klein, MD and Katja Lohmann, PhD
Funding agency: Bachmann Strauss Dystonia & Parkinson Foundation
Funding period: 2011
Amount: 35,500 €

“Molecular analysis of the THAP1 gene and its role in dystonia”

Principal Investigator: Katja Lohmann, PhD
Funding agency: German Research Foundation (DFG)
Funding period: 2010-2012
Amount: 220,000 €

“Abundance and cellular localization of wildtype and mutant SGCE in human skin fibroblasts and induced pluripotent stem cell‐derived neurons”

Principal Investigator: Anne Grünewald, PhD
Funding agency: Dystonia Medical Research Foundation
Funding period: 2011-2012
Amount: 76,000 €

“Characterization of endophenotypes in focal task-specific dystonia”

Principal Investigator: Christine Klein, MD
Funding Agency: Dystonia Coalition (NINDS)
Funding period: 2011-2012
Amount: 35,500 €

“New insights into the genetics and molecular pathways of XDP”

Principal Investigator: Ana Westenberger, PhD
Funding agency: Bachmann-Strauss Dystonia & Parkinson Foundation
Funding period: January 2012 to December 2012
Amount: 50,200 €

“Identifizierung und Charakterisierung von genetischen Risikofaktoren der Dystonien”

Principal Investigator: Katja Lohmann, PhD
Funding agency: Renate-Maaß-Foundation
Funding period: 2012
Amount: 5,000 €

“Genomics of Recessive Parkinsonism – NGFN‐plus”

Principal Investigator: Christine Klein, MD
Funding agency: Federal Ministry of Education and Research (BMBF) 
Funding period: 2008-2013 
Amount: 340,000 €

“Genetic risk factors of musician’s dystonia”

Principal Investigator: Christine Klein, MD
Funding agency: German Research Foundation (DFG) 
Funding period: 2010-2013 
Amount: 295,000 €

“Epidemiology of non‐motor symptoms in Parkison disease: Frequency, characteristics, specificity, and course”

Principal Investigator: Meike Kasten, MD
Funding agency: German Research Foundation (DFG) 
Funding period: 2010-2013 
Amount: 300,000 €

“Transcranial ultrasonographic evaluation of the basal ganglia in DYT1, DYT11, and DYT12 dystonia”

Principal Investigator: Christine Klein, MD
Funding agency: Bachmann-Strauss Dystonia & Parkinson Foundation
Funding period: 2012 - 2013
Amount: 20,000 USD

“Modulation of response inhibition mechanisms of action control: a combined TMS-fMRI study in healthy individuals”

Principal Investigator: Norbert Brüggemann, MD
Funding agency: German Research Foundation (DFG)
Funding period: 2011-2013
Amount: 50,000 €

“8th Annual Meeting of GEO-PD (Genetic Epidemiology of Parkinson's Disease) in Lübeck”

Principal Investigator: Christine Klein, MD
Funding agency: German Research Foundation (DFG)
Funding period: 2013
Amount: 24,000 €

“Quantitative proteomics approach to elucidate the impairment of mitophagy in a human cellular model of Parkinson´s disease”

Principal Investigator: Ana Djarmati, PhD
Funding Agency: Fritz Thyssen Foundation
Funding period: 2011-2013
Amount: 180,000 €

“The role of the PINK1/Parkin pathway in the regulation of mitophagy”

Principal Investigator: Anne Grünewald, PhD
Funding agency: Fritz Thyssen Foundation
Funding period: 2012 - 2014
Amount: 125,000 €

“Mitochondrial mutations in neurodegenerative diseases”

Principal Investigator: Anne Grünewald, PhD
Funding agency: German Research Foundation (DFG)
Funding period: 2012 - 2014
Amount: 54,000 €

“Multidisciplinary X-linked Dystonia-Parkinsonism Workshop”

Principal Investigators: Prof. Dr. Christine Klein, Dr. Aloysius Doming, Dr. Ana Westenberger
Funding agency: Fritz Thyssen Foundation
Funding period: May-June 2014
Amount: 9,700